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Even further work on the mechanisms of telomerase regulation, telomere-binding protein function, plus the interplay concerning telomeres along with other cellular compartments should enormously aid our understanding of telomere-relevant diseases and our look for suitable diagnostic and therapeutic instruments.The synthesis of the telomere entails a

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the telomerase subunit Est1p has lately been revealed for being able to converting one-stranded telomeric G-abundant DNA right into a G-quadruplex structure in vitroTelomeres are very conserved tandem nucleotide repeats that contain proximal double-stranded and distal single-stranded regions that in elaborate with shelterin proteins manage defense

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